These were catagories designed by Stewart and Medow to subtype based on cutaneous blood flow.
The low flow subtype were almost exclusively female, generally had low body mass index, low blood volume and resting vasoconstriction but felt profoundly worse when given IV Vitamin C to improve flow-mediated dilation. These were asdociated with excessive angiotensin II in serum which more recently appears tied in some to autoantibodies agonising Angiotensin ii receptor type 1 (AT1-r) - MAS aabs suppress renin aldosterone which is believed to partially explain the volume deficits.
High flow have excessive blood flow and microvascular filtration in hands and feet which were warm to touch.
Normal flow was the most common and pooled exclusively in the stomach venous circulation.
The resulys suggest that all three forms had pooling in one region.