Hi Steph, I have Marfan's and by looking at family pictures, and talking to relatives, several people in my dad's family probably had it or have it, but it hasn't been a problem for us. Although a couple of my aunts, and great aunts have had valve replacement surgery because of MVP. I simply get an echo done once a year, and see Dr. Grubb and a local cardiologist every 6 months to get my valves checked. Many medical historians think Abraham Lincoln had Marfan's, so I always felt like I was in good company! Do you have it, or your kids? Or just relatives? I know it can be bad in some cases, but my docs don't think it will be any more damaging in me than my joint hypermobility or POTS. It's just something we keep an eye on. Take Care -Steph