Libby and Wendy..... I had never had any vertigo before. It started on about the 6th day of Midodrine. It was positional vertigo. IE when I rolled over in bed in the AM it felt like I was on a boat and even when I stood up, it continued for a few minutes and then would go away completely. The Midodrine was so great because I could be up and functioning again, but I was afraid if I continued the Midodrine, it might cause permanent vertigo. After I dc'd the Midodrine, the positional vertigo very gradually disappeared. It's bee 6 weeks now and it's almost completely gone. That part doesn't make any sense to either because Midodrine has a short half life is is supposedly out of your body very fast. I also never took it past 1:00 PM, yet it took six weeks for the side effect to go away. I don't understand that.