Yeah, my body seems to be getting even more sensitive to meds... I've been allergic to penicillin since I was a baby, recently i was on celexa for the syncope and I got an aleergic reaction from that and now the cymbalta. anaphylaxing- I don't know much about mast cell disease. What is it and does it relate to having allergic reactions? Thanks everyone for all of your posts, they have all been very helpful!