Outaker
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Posts posted by Outaker
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Hope this answers your question-
- The overall cardiovascular response is increased cardiac outputand systemic vascular resistance, which results in an elevation in arterial blood pressure. Heart rate, although initially stimulated by norepinephrine, decreases due to activation of baroreceptors and vagal-mediated slowing of the heart rate in responses to the elevation in arterial pressure.
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22 hours ago, p8d said:
happy to hear mate
8 hours ago, FileTrekker said:I've found the Mag won't reduce the number of ectopics, just make them feel a bit softer. Combined with taurine, after a week or so the senstion is softer still and the numbers of them started to drop. I still get loads of them but it's certainly better than without.
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My resting NE was 500 and standing was 1700.
Was wondering what everyones regimen is for hyper pots treatment?
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4 minutes ago, p8d said:
Thanks @Outaker How is it going? I was surprised that you are on both Tenex and Cardiodopa. I think I am missing something? Is the peripheral action against dopamine or some other catecholamine than norepinephrine (which the Tenex should hit?)? Please let us know how it helps or not. Thanks.
Tenex is Guanfacine which Is an Alpha 2 Agonist like clonidine. Carbidopa is a Parkinsons drug but it has been found to block perpipheral dopamine levels which prevents conversion to norepinephrine so in essence it lowers norepi in tissues not the brain. losartan is angiotesin 2 blocker.
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I have began the routine. I am Hyper Pots I am currently taking Carbidopa Tenex and Losartan
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Thats quite odd.. I have never heard of this medicine being perscribed for hyper pots
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Indeed I will. Anyone try this before?
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Do not take cold showers take lukewarm showers and your bp won’t gonup.
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Bump
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Peripheral resistance. Diastolic goes up to try to get blood to your head. What meds are you on?
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Beta blockers are dangerous for hyper pots people. Unopposed alpha is bad.
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Hmm might be on to something here http://grantome.com/grant/NIH/R01-FD004772-01A1
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Don’t care about insurance at this point I’ll lay anything I have seen the top doctors everywhere and they have no idea how to control my tachy and bp. Beta blockers make me so bad and the only thing that works barely is clonidine
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I have hyper pots and saw Dr. Goodman yesterday at the mayo clinic. He perscribed Carbidopa ?? isnt that a dopamine booster??
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6 hours ago, FileTrekker said:
What is Rauwolfia? I'm not sure why anyone would even be taking it / want to based on that?
How does it relate to reserpine / what is that?
Rauwolfia drains norepinephrine which prevents huge surges in blood pressure.
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Rauwolfia’s effects on the heart include decreasing myocardial excitability, inhibiting atrial-ventricular conduction, and extending the refractory period of the heart rhythm.1
Much of the medicinal effects of Rauwolfia serpentina and Rauwolfia vomitoria have been attributed
to the hypotensive indole alkaloid reserpine.2Additional alkaloids found in Rauwolfia roots include the indoles ajmaline, ajmalicine, raubasine, imethylajmaline, methylisoajmaline, hydroxysarpagine, yohimbinic acid, and isorauhimbinic acid.3 The constituent ajmaline is thought to be antiarrhythmic.4Before the advent of the current pharmaceutical options for hypertension (beta blockers, calcium channel blockers, and angiotensin-converting Inhibitors), reserpine was a mainstay in the management of hypertension. Reserpine acts via the CNS to reduce sympathetic tone, increase parasympathetic activity, and help normalize blood pressure, especially when because of stress and sympathetic nervous responses, as it may partially block adrenaline receptors.5 Reserpine’s ability to block adrenoreception on blood vessels can reduce stress-induced vasoconstriction contributing to hypertension or heart palpitations.
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Blizzard. You need to take 5htp or go on Zoloft in my opinion. You need your synapses drained of norepinephrine-
THese are just my opinions-
Can you do the clonidine patch? I know you take the pills.I am trying a new Herb to see if it helps. Rauwolfia -
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Nope just started researching this condition due to the adrenaline surges. I am looking to prevent any surges again in the future.
Rauwolfia drains norepinephrine from your synapses by 70 percent. The first hypertension drug developed Reseprine was based on this herb's alkoloids.
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On 2/28/2019 at 10:30 AM, FileTrekker said:
Thanks. Yes I have no intention of taking the Bisoprolol, if for no other reason than I just know they'll floor me and I can't afford the time off work.
I'm also seeing some limited success on magnesium and taurine supplements and I'm gonna try coconut water too. If it gets more desperate then I may consider it. I feel doctors are too quick to just jump to beta blockers and send you on your way. My POTS is manageable without the BB thankfully and I have bradycardia anyway. So to my mind it's not a worthwhile risk currently.
15 hours ago, AngieP said:Hi @Outaker,
I'm afraid I haven't worked out a way to totally stop the POTS attacks from occurring.
For me, I find that if I get lots of rest, eat a healthy clean diet, and incorporate exercise (light strength training - no cardio), I am pretty stable. As soon as I mentally or physically over do it, I can find myself in a nice big POTS flare up.
I've also been on a daily beta-blocker for the last five years that has helped me a lot.
Do your attacks occur in clusters too? The one I'm in has been going for almost three weeks - I'm having an attack every second day which is a lot for me.
Cheers,
AngieHey ANgie have you tried rauwolfia?
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On 3/12/2019 at 3:00 PM, AngieP said:
@Pistol - such a good description of an adrenaline surge.
I'm in the midst of a POTS storm at the moment after a pretty good run.
The chest pain that comes with the attacks is particularly bad at the moment. I was wondering if anyone has explained to you what causes the chest pain? My cardiologist doesn't think it is cardiac in origin but I think it would help me to deal with the pain if I understood it better.
Also do you find your attacks occur in clusters?
Thanks!
Angie how have you stopped them from occurring?
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A hyper pots with iv fluids.. go figure
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Ivabradkne and clonodine is the usual combo for hyper pots
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I suggest you ask your doctor for Labetalol or clonodine, to address the adrenaline surges.
Episodes of slow heart rate
in Dysautonomia Discussion
Posted
Beta blockers can make things a lot worse so be careful -