ramakentesh Posted March 26, 2013 Report Share Posted March 26, 2013 1. POTS and its association with small fiber neuropathy - the 'neuropathic' subgroup:* 'Distal sudomotor findings in postural tachycardia syndrome.'http://www.ncbi.nlm.nih.gov/pubmed/20035362* 'The Pathophysiology of Neuropathic and Non-Neuropathic Postural Tachycardia Syndrome'http://www.neurology.org/cgi/content/meeting_abstract/78/1_MeetingAbstracts/P05.203* 'Autonomic Innervation in Neuropathic and Non-Neuropathic Postural Tachycardia Syndrome'http://www.neurology.org/cgi/content/meeting_abstract/80/1_MeetingAbstracts/S37.0052. POTS and its association with epigenetic Norepinephrine transporter protein supression - the 'NET deficiency' subgroup:* 'Altered Sympathetic Nervous Reactivity and Norepinephrine Transporter Expression in Patients with Postural Tachycardia Syndrome'http://circep.ahajournals.org/content/1/2/103* 'Epigenetic modification of the norepinephrine transporter gene in postural tachycardia syndrome'http://www.ncbi.nlm.nih.gov/pubmed/227234373. POTS and its association with decreased blood volume, reduced aldosterone and elevated angiotensin II - the 'Low Flow' subgroup:* 'Renin-Aldosterone Paradox and Perturbed Blood Volume Regulation Underlying Postural Tachycardia Syndrome'http://circ.ahajournals.org/content/111/13/1574* Increased plasma angiotensin II in postural tachycardia syndrome (POTS) is related to reduced blood flow and blood volume'http://www.clinsci.org/cs/110/cs1100255.htm* Abnormalities of Angiotensin Regulation in Postural Tachycardia Syndromehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050076/* Defects in Cutaneous Angiotensin Converting Enzyme 2 and Angiotensin-(1–7) Production in Postural Tachycardia Syndrome'http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765216/ POTS as a manifestation of abnormal cerebral autoregulation: 'Decreased upright cerebral blood flow and cerebral autoregulation in normocapnic postural tachycardia syndrome' http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724195/ 'Postural neurocognitive and neuronal activated cerebral blood flow deficits in young chronic fatigue syndrome patients with postural tachycardia syndrome.'http://www.ncbi.nlm.nih.gov/pubmed/22180650 Quote Link to comment Share on other sites More sharing options...
ramakentesh Posted March 26, 2013 Author Report Share Posted March 26, 2013 As background, the angiotensin II discovery and its connection with the renin-aldosterone paradox was considered to be the major finding in the last six years on POTS.In the new newsletter it is interesting that the recent paper on the acquired/epigenetic mechanism in some POTS patients was considered by the doctor to be the 'most interesting' recent research.Steady progress is being made. Quote Link to comment Share on other sites More sharing options...
issie Posted March 26, 2013 Report Share Posted March 26, 2013 Thanks for the links. Gives me something more to read when I can't sleep at night. Quote Link to comment Share on other sites More sharing options...
Angela Posted March 26, 2013 Report Share Posted March 26, 2013 so hey Rama, what's your opinion on pots and seizures. simple focal or full blown. do you think it could be related or just a happenstance. Quote Link to comment Share on other sites More sharing options...
ramakentesh Posted March 26, 2013 Author Report Share Posted March 26, 2013 No association unless the sympathetic excess from POTS is somehow decreasing the seizure threshold. Quote Link to comment Share on other sites More sharing options...
voner Posted March 29, 2013 Report Share Posted March 29, 2013 Rama, thx a lot! what is the newsletter you are referring to?........... "In the new newsletter" Quote Link to comment Share on other sites More sharing options...
ramakentesh Posted March 29, 2013 Author Report Share Posted March 29, 2013 The diner winter newsletter. Quote Link to comment Share on other sites More sharing options...
blueskies Posted March 29, 2013 Report Share Posted March 29, 2013 Thanks rmamkentesh. Quote Link to comment Share on other sites More sharing options...
ramakentesh Posted March 29, 2013 Author Report Share Posted March 29, 2013 Mama kentesh? I like it... Quote Link to comment Share on other sites More sharing options...
Guest Alex Posted March 29, 2013 Report Share Posted March 29, 2013 Mama kentesh, better yet daddy kentesh - I never got the chance to congratulate you on your baby so here it is, congrats! I bet POTS fatherhood has its 'perks', how are you holding up?To the point though - thanks for posting those links. Most useful.Alex Quote Link to comment Share on other sites More sharing options...
Angela Posted March 29, 2013 Report Share Posted March 29, 2013 the diner newsletter ha ha! Quote Link to comment Share on other sites More sharing options...
ramakentesh Posted March 29, 2013 Author Report Share Posted March 29, 2013 Thanks. Yeah going well. Appreciate the kind words. Pots is being annoying at the moment but it won't last. Quote Link to comment Share on other sites More sharing options...
ramakentesh Posted March 29, 2013 Author Report Share Posted March 29, 2013 We don't have diners in Australia. I miss those hush puppies and hash browns! Quote Link to comment Share on other sites More sharing options...
ramakentesh Posted March 29, 2013 Author Report Share Posted March 29, 2013 And jalapeno poppers! Quote Link to comment Share on other sites More sharing options...
Guest Alex Posted March 29, 2013 Report Share Posted March 29, 2013 my mouth is watering now, thanks guys! Quote Link to comment Share on other sites More sharing options...
Angela Posted March 29, 2013 Report Share Posted March 29, 2013 f yeah jalepeno poppers! i loved the zuchinii stuffed. sorry man that u feel like ****. oh well, love u bro but had those days def. Quote Link to comment Share on other sites More sharing options...
ramakentesh Posted March 29, 2013 Author Report Share Posted March 29, 2013 Im not too bad now compared to where I was two week ago. It will pass. Always does in my case - would just prefer a few years in between rather than a few months Quote Link to comment Share on other sites More sharing options...
ramakentesh Posted March 29, 2013 Author Report Share Posted March 29, 2013 Jalapeno poppers with a nice amber ale. MMM...memories... Quote Link to comment Share on other sites More sharing options...
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