ramakentesh Posted January 22, 2005 Report Share Posted January 22, 2005 I was lucky enough to meet a senior medical researcher at a work function recently. He was involved in studies on autoimmune conditions and their causes for many years, and although he has moved on into other fields, was still abreast of recent developments in that area.When i talked to him about POTS - which he had never heard of at all - and its many symptoms, he was particularly interested in the relating hypovolumia that this condition and CFS also shares. In his opinion, there could be literally hundreds of conditions that could causes this, most of them being unknown - and that the hypovolumia would be a compensatory response to any of these numerous conditions. He could see many biochemical pathways that could be influencing this phenomenon. On one hand you might have dietary, viral or genetic problems that are causing your kidneys to excrete too much water. On the other hand the renal system may be acting to compensate for a problem elsewhere. For instance our arteries have stretch detecting receptors that act along with many other systems to regulate blood volume and hence pressure. I dont know where the current research is on these receptors but I'll bet we dont totally know how they operate. It is quite likely that they react to the enzymes produced by the surrounding tissue when under stress. If you had a defect in these cells making your vessels weak then your low blood volume would be a very desirable compensatory mechanism that the body has utilised to keep you alive. In all he was very worried about people taking meds to increase blood volume if there is a biological problem that is occuring that is making or bodies lower blood volume to compensate.The most interesting point he made was that when he was involved in this area, the current thinking was that many of these mysterious conditions might be viral in origin. He was told that there were currently about 40 virus known to have been integrated into the DNA of the majority of us. He explained that Researchers believe that in the end we will find out that their numbers are in the 1000s. Under the appropriate conditions these virus can activate and manipulate their host into reproducing them. This was what they were and still are investigating with a huge number of health problems. Quote Link to comment Share on other sites More sharing options...
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