misstraci Posted July 30, 2011 Report Share Posted July 30, 2011 I'm sorry if I am repeating a question that has been asked but I was curious about what midodrine does to the heartrate. I read that it can cause bradycardia and my SSRI says the same thing. Will the two of them together cause like a super low heartrate? Have you heard of this? and do you take midodrine as well as an SSRI? Quote Link to comment Share on other sites More sharing options...
yuliya Posted July 30, 2011 Report Share Posted July 30, 2011 I didn't notice a big difference with the heart rate when I took Midodrine, also I am not on an ssri either. Quote Link to comment Share on other sites More sharing options...
Rachel Posted July 31, 2011 Report Share Posted July 31, 2011 I haven't noticed a change in heart rate while taking midodrine. All it does for me is raise my blood pressure.Rachel Quote Link to comment Share on other sites More sharing options...
Csmith3 Posted July 31, 2011 Report Share Posted July 31, 2011 At first, my heart rate only went down about 10 points on midodrine. My blood pressure went up and I felt much, much better.Unfortunately, after a few weeks, my heart rate gets lower and lower and I feel worse than without midodrine. I'm not on a SSRI, but I am on an antiarrhythmic. I tried all sorts of combinations of midodrine with or without other drugs, but could not stop my heart rate dropping after a few weeks. The metabolism of midodrine does depend on many factors, including other drugs you are taking which may use the same enzyme to break down the drug. In my case, the drug was active for way too long but there wasn't anything I could do to speed up the metabolism. I guess this is a long winded way of saying, you'll have to try it to see what happens. Quote Link to comment Share on other sites More sharing options...
kayjay Posted August 1, 2011 Report Share Posted August 1, 2011 Haven't started it yet but my cardiologist just suggested I try this. I have to have surgery next weeks so I haven't started yet, but I am on Cymbalta. She warned me to start with a small dose and to check my bp. She said that it will increase supine bp. I have high bp so I will be using it very carefully. Quote Link to comment Share on other sites More sharing options...
misstraci Posted August 1, 2011 Author Report Share Posted August 1, 2011 Thank you all for sharing with me !!! Quote Link to comment Share on other sites More sharing options...
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