Altitude sickness is a possibility, though not everyone experiences it. Symptoms like dizziness and a rapid heart rate can occur. If you do feel unwell, rest, stay hydrated, and consult with your healthcare provider. They may recommend over-the-counter medications like ibuprofen. Denver is known for its sunny days, so remember to use sunscreen and wear sunglasses to shield yourself from the intense sun at higher altitudes. If you have medications for your POTS, ensure you have an ample supply with you and take them as prescribed. I've been a frequent traveler myself and recently discovered some useful tips for saving on business-class flights. If you're interested, you can learn more about securing discounted business-class tickets for your travels.