ramakentesh Posted March 19, 2013 Report Share Posted March 19, 2013 I find the effects of licorice very interesting.WIthin a minute of me drinking its tea I get immediate benefit for all my POTS symptoms and notice the veins in my hands become more visible rather than less which is interesting.It is often reported that its benefit comes purely from its sodium loading enhancing properties via psuedoaldosteronism - promoting volume expansion.However, the effects i get from it are always acute and always straight away so I decided to look at alternative actions:Reduces the expression of ROS superoxide free radicals and inductible (immune system) nitric oxide:http://www.ncbi.nlm.nih.gov/pubmed/21734629http://connection.ebscohost.com/c/articles/67736983/licocalchone-c-extracted-from-glycyrrhiza-glabra-inhibits-lipopolysaccharide-interferon-inflammation-by-improving-antioxidant-conditions-regulating-inducible-nitric-oxide-synthase-expressionanti inflammation - inhibiting prostaglandin D2 and Cox-2:http://lib.bioinfo.pl/paper:20864324Apparently INCREASES nitric oxide production in endothelial cells:http://www.cabdirect.org/abstracts/20083330424.html;jsessionid=681FD4739A44F22CA5C08519BBE48968?gitCommit=4.13.20-5-ga6ad01aOr does it REDUCE endothelial nitric oxide (eNOS) and NAPHD related oxidisive stress?:http://www.ncbi.nlm.nih.gov/pubmed/18841076Reduces levels of angiotensin IIhttps://docs.google.com/viewer?a=v&q=cache:n9lKwZzloWsJ:tobacco-information.bhp.doh.gov.tw/toxicfolder/039.%25E9%2587%2587%25E7%259B%259F-%25E5%2582%2591%25E5%25A4%25AA%25E6%2597%25A5%25E7%2585%2599/Tox-Profile-010.pdf+Glycyrrhiza+glabra+angiotensin+at1&hl=en&gl=au&pid=bl&srcid=ADGEEShVSE5UypVcNlkTS7O-b5nwwKmoNB6f5-WyhekwtBV49jJ1HzK5koA_CCRKPnLgCHI9uwbfWisx7QsuzNTwHwtCKujJJG05p9LjrEpkAt73LzywKEVAmq6uAPLlwpB8ztGhskRY&sig=AHIEtbS9-nWa1cwhqcsqnLFOVJwmsA2gnQEffects on NF Kappa:http://www.ncbi.nlm.nih.gov/pubmed/17259331More on reducing endothelial nitric oxide:http://circ.ahajournals.org/content/103/25/3129.full.pdf Quote Link to comment Share on other sites More sharing options...
ramakentesh Posted March 19, 2013 Author Report Share Posted March 19, 2013 Causes or potentially can cause cerebral vasoconstriction:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995386/ Quote Link to comment Share on other sites More sharing options...
ramakentesh Posted March 19, 2013 Author Report Share Posted March 19, 2013 More interesting - cerebroprotextive effects in cerebral hypoxia:https://docs.google.com/viewer?a=v&q=cache:a1iZFKMp3RAJ:www.doaj.org/doaj?func%3Dfulltext%26aId%3D298556+Glycyrrhiza+glabra+norepinephrine+transporter&hl=en&gl=au&pid=bl&srcid=ADGEESh5_YZMMQP0IREAJjzC7LyKN8eE5qZvc7KhDHgolrMXD6WqNWxTn4tDXvsI-31LHFGzzll7L50vU00PlyfiukkZG16W4oVQh4kKcvzL_12j1w3buKitAB1B0umI7l9sv8NPIPuD&sig=AHIEtbT3rR6H2MYTuX6R67t8HIMVz0Vtcg Quote Link to comment Share on other sites More sharing options...
AussieOI Posted March 19, 2013 Report Share Posted March 19, 2013 Vety interesting - I will be getting some licorice tea Quote Link to comment Share on other sites More sharing options...
Kellysavedbygrace Posted March 19, 2013 Report Share Posted March 19, 2013 I have wondered why you are such a proponent of licorice. I have tried it in many forms, tea, dry root herb, and of course candy. I have not noticed any immediate improvements or downsides like you have and wonder have I just been missing them? The clinical evidence you shared makes me want to analyze more specifically. I have elevated Prostaglandin D2 and cannot tolerate aspirin so to learn that licorice might help is very interesting.Good thing I like the taste of it.Sounds like you prefer the tea. (and you may have answered this in a previous post but....) which forms/brands do you observe the most benefit? Is the candy even helpful?Also, you said you get "immediate relief of all your POTS symptoms"- what does that mean? Which symptoms? Quote Link to comment Share on other sites More sharing options...
bellgirl Posted March 19, 2013 Report Share Posted March 19, 2013 I loved licorice even before I knew I had POTS....hum...our bodies do take care of themselves. Thanks Rama...interesting Quote Link to comment Share on other sites More sharing options...
issie Posted March 19, 2013 Report Share Posted March 19, 2013 I'm glad you put up some reports of the BAD effects that this could have on SOME people too. But, how many of you read the whole thing to find out if you were one that licorice would not be such a good fit for? Those with hypertension and low NO this would not be so good for. It does cause fluid retention and salt retention - it lowers potassium levels, it lowers renin and aldosterone levels along with angiotension II levels (some of us are already low in this). As with florinef - since licorice has similiar properties - it can affect your adrenals and cortisol levels. It affects kidney function and can raise blood pressure and cause edema. There is one report here of it causing severe headaches because of the vasoconstricting action. Some people do need to raise blood pressure - and lower NO. (Although, there were conflicting reports about NO being lowered in all areas of the body. But, more reports showing that overall NO is lowered with licorice.) But, not everyone does. So, although this may be wonderful for some. It will NOT be wonderful for all of us. Issie Quote Link to comment Share on other sites More sharing options...
cmreber Posted March 19, 2013 Report Share Posted March 19, 2013 It's interesting you mentioned potassium, Issie. I have struggled with low potassium for some reason over the past couple of years and my doctor says to stay away from licorice. Doesn't matter too much, I hate the black kind anyway lol, always have...even black jellybeans! But, it is great that it might help some people with their symptoms! Quote Link to comment Share on other sites More sharing options...
dpeeps Posted March 20, 2013 Report Share Posted March 20, 2013 I had no idea that licorice could be beneficial for some people with POTS. <Still learning - less than 1 year since diagnosis> However, this is very interesting. First, let me admit - I have always 'liked' black licorice (the Austrailian kind with actual licorice extract). I noticed that I crave it particularly before and during mensruation. These are when my POTS symptoms are at their very worst. During this time, if there is black licorice in the house, I cannot stop eating it!! LOL. Now I will have to try the tea.... thanks for posting this topic. Quote Link to comment Share on other sites More sharing options...
MomtoGiuliana Posted March 20, 2013 Report Share Posted March 20, 2013 Some brands of licorice candy contain molasses, making it a rich source of potassium and iron--and you might actually crave too during menstruation. And some "licorice" candy contains only anise seed flavor -- no real licorice in the candy. I only know this b/c I have also always loved licorice--although I am partial to chocolate too Quote Link to comment Share on other sites More sharing options...
looneymom Posted July 3, 2013 Report Share Posted July 3, 2013 Are you still using licorice? My son is finally off florinif but I want to have an natural alternative to try if his blood pressures start to drop again. My son really does not like tea or licorice candy. Does this stuff come in capsules? Starting to go through some of your articles now. My son has been off his flornif for a week. So far his blood pressures are staying up. Any suggestions? Quote Link to comment Share on other sites More sharing options...
MomtoGiuliana Posted July 3, 2013 Report Share Posted July 3, 2013 You can get deglycerized licorice in capsules. People often use it when they have heartburn. I tried it a long time ago for a weird bout of heartburn I was experiencing and it helped more than any over the counter antacid. http://healthyeating.sfgate.com/deglycerized-licorice-7022.htmlYou may want to read more about it at this link. Pure licorice in too large amounts can lower potassium and increase blood pressure, according to what I understand. So perhaps it acts similarly to florinef? Quote Link to comment Share on other sites More sharing options...
Guest Alex Posted July 3, 2013 Report Share Posted July 3, 2013 I'll bump an older thread on licorice. The first article posted by Rama in that thread is very detailed and it's worth reading if you're looking into licorice.Alex Quote Link to comment Share on other sites More sharing options...
americaneagle32 Posted July 17, 2013 Report Share Posted July 17, 2013 I read that licorice can help. Do you think candy would be just as effective as tea? Quote Link to comment Share on other sites More sharing options...
Guest Hanice Posted July 17, 2013 Report Share Posted July 17, 2013 Maybe if its mostly licorice and not licorice flavor. I wish I could take this stuff but I probably shouldn't since my potassium is low. :-( and my bp gets high Quote Link to comment Share on other sites More sharing options...
Guest Hanice Posted July 17, 2013 Report Share Posted July 17, 2013 http://m.voices.yahoo.com/licorice-side-effects-avoid-eating-licorice-2270618.html Quote Link to comment Share on other sites More sharing options...
Guest wishing&hoping Posted July 18, 2013 Report Share Posted July 18, 2013 That's interesting. My prostaglandin levels were low; now wonder whether it was (is) the licorice rather than lab error as Afrin suspects. I take the capsule form but take it on and off because I already have chronic diarrhea and worry about it lowering my potassium. Don't need more electrolyte challenges; already have enough challenges . Quote Link to comment Share on other sites More sharing options...
MomtoGiuliana Posted July 18, 2013 Report Share Posted July 18, 2013 I take the capsule form...If it is in capsule form perhaps it is deglycerized? If so the potassium lowering effect has been removed. Quote Link to comment Share on other sites More sharing options...
Guest wishing&hoping Posted July 18, 2013 Report Share Posted July 18, 2013 No, it's just the herb in a capsule from my naturopath. Nice try... Quote Link to comment Share on other sites More sharing options...
Suthrngal Posted July 18, 2013 Report Share Posted July 18, 2013 Can you drink traditional Medicinals organic licorice root tea for this purpose? Quote Link to comment Share on other sites More sharing options...
looneymom Posted August 7, 2013 Report Share Posted August 7, 2013 bump! Quote Link to comment Share on other sites More sharing options...
Guest maia Posted August 7, 2013 Report Share Posted August 7, 2013 Here is a list of spices high in potassium for those of you with K concerns. Suthrngal, that tea is real licorice so yes, its what is being talked about here. Quote Link to comment Share on other sites More sharing options...
looneymom Posted December 24, 2013 Report Share Posted December 24, 2013 Bump up Quote Link to comment Share on other sites More sharing options...
gjensen Posted December 25, 2013 Report Share Posted December 25, 2013 I am on day six of improved symptoms. Right now, I am giving much of the credit to licorice. Knock on wood, because I am due a crash. For the last six days my heart rate has been tempered, and my head symptoms have been tolerable. Quote Link to comment Share on other sites More sharing options...
ramakentesh Posted December 28, 2013 Author Report Share Posted December 28, 2013 Its good stuff. But tolerance becomes an issue after about two months. Im no longer on it but its worth a shot for anyone struggling (I mean more than usual) Tlak to a doc and all that. Quote Link to comment Share on other sites More sharing options...
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