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What Does This Statement From The Cleveland Clinic Mean?


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I was just at the Cleveland Clinic website who apparently has an autonomic center, and this was on their website

"

What is the prognosis?

The outlook for patients with dysautonomia depends on the particular diagnostic category. Patients with chronic, progressive, generalized dysautonomia in the setting of central nervous system degeneration have a generally poor long-term prognosis. Death can occur from pneumonia, acute respiratory failure, or sudden cardiopulmonary arrest in such patients."

What does that central nervous system degeneration mean? Can someone please elaborate on that?

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Central nervous system refers to the brain and spinal cord as opposed to the peripheral nervous system which is the nerves going to the muscles, etc. So central nervous system degeneration would refer to some process that is causing damage to the brain and spinal cord.

My sister in law had a life-long SEVERE seizure disorder which eventually did so much damage to her brain that it caused her to have generalized dysautonomia and did in fact lead to her death. (Her seizures were so severe they caused mental retardation as a very young child. We're talking 5-6 grand mal seizures a day.)

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