I have had POTS episodes for over 15 years, however was just diagnosed with a tilt table test. I had 3 good years, while treated for sinus infections with Prednesone. It seems that none of my MD's have heard of treating POTS with prednesone, so now that I no longer have sinus infections, I am having multiple POTS episodes, and my quality of life has gone down fast. Has anyone ever heard of a link between POTS and improvement on Prednesone? What tests were done to prove that this method would work for you? Any thoughts would be helpful.