ShakeyTheOwl

Am so sorry for your loss, and have had same loss. Had severe toxemia, and was in hospital for last three months, ending with placenta abruption. Am not sure if any of that triggered stress in body to develop dysautonomia later in life, but do think life traumas can have effects physically. My onset of dys was sow grade fever, lumps in lymph nodes, drenching sweats and weight loss. Initially lymphoma was possibility, and went through biopsies and other. I did have thyroid testing, but that came back normal. Wishing you nothing but the best, and hope answers, solutions and healing come soon.

Five parrots and two dogs :-) Being housebound, they truly are what keeps me going at times, always with love. I miss greatly not being able to do wild and domestic avian rescue/rehab, but try to continue advocacy and education via internet. The animals definitely teach me so much, and are incredible at being aware/gentle on tough days. My parrots, their intelligence never ceases to amaze me. And they are very good listeners :-)

Ordered one through Amazon. Thirty degree wedge and is of memory foam with washable cover. I read through many reviews and am pleased with it. (raising our bed was not option ) It has taken some getting use to. It's nice for resting and reading in bed.

Under "Related Research" are a few interesting pieces: http://www.ldners.org/research.htm#DM Related Research: Imiquimod, An Immune Response Modifier, Is Dependent On 
 The OGF-OGFr Signaling Pathway - MedicalNewsToday.com 7/27/08 
 Exp Biol Med, Aug 2008 Abstract The role of glutamate transporters in neurodegenerative diseases and
 potential opportunities for intervention.
 Neurochem Int. 2007 Apr 19, Sheldon AL, Robinson MB. A team including JS Hong at the National Institutes of Health has been researching the neuroprotective effects other compounds similar to Naltrexone Role of Microglia in Inflammation-Mediated Neurodegenerative Diseases: Mechanisms and Strategies for Therapeutic Intervention

 Role of nitric oxide in inflammation-mediated neurodegeneration 

 Inhibition by naloxone stereoisomers of beta-amyloid peptide (1-42)-induced superoxide production in microglia and degeneration of cortical and mesencephalic neurons

 Dextromethorphan Protects Dopaminergic Neurons against Inflammation-Mediated Degeneration through Inhibition of Microglial Activation

ok, it's been a while since I have visited this highly recommended Naturopath (people from all over our region recommended her highly because of her background) But this is basically how she explained to me LDN and compounds it at her office, personally. The way she explained it was how LDN was manufactured and used in the UK (England) for Heroin overdoses, it was coincidence that it helped other illnesses including HIV, and Cancer, research was done in UK regarding, but not here in States. (so there may be further documents in UK regarding studies on LDN) Ultram and Tramadol are the same drug, they are not actual opiates, such as morphine, demerol, etc. The contradiction is regarding LDN and narcotics is that the LDN would stop the opiod from working. (and briefly, short acting) She mentioned a few times how short acting the LDN is, and for prescribed chronic illness it is very very low dose. The above link I had posted, regarding LDN, the website is maintained by a friend of family, she is also a medical advocate. (we've had some interesting discussions regarding auto immune, cancer, diet, food allergies, medications, etc similar to things I've seen few others post in here regarding alternative therapies) I did do the LDN and Tramadol, and had no trouble, but can say at that time the major thinking of my illness was Lymphoma or type of blood cancer, as it has turned out, it is Dysautonomia, which was not looked at. (OH, PAF, with possible Parkinsonian cause) (the Hemotologist/Oncologist wrote me up for seeing a Naturopath in his chart notes, and for taking LDN which he admitted he knew nothing of, but wanted to learn more regarding, his eyes perked up when I told him that this Naturopath had spent twenty years in Cancer research at Fred Hutch) Since Dysautonomia has so many different possible causes, (and no cures) it may be helpful for the ones with auto-immune based, given the LDN research supports some benefit in regards, as well CFS. Here's another link I grabbed from the Naturopath's website: http://www.ldners.org/resources.htm#Forums Another one explaining the Narcotic/Opiod and other: http://www.digitalnaturopath.com/treat/T74481.html

Hi! have had similar with Tramadol as you describe Issie. It was helpful when it worked. This link to LDN? and wondering if maybe there is any answers to questions? http://www.lowdosenaltrexone.org/further_q_and_a.htm Also, couple years back, had seen Naturopath (she also holds MD, and her ND from Bastyr University, and did 20 years research at Fred Hutchinson Cancer in Seattle) She told me that it was very, very short acting in our system, and at that time was taking Tramadol, she stated I could take it during day, but not 6 hours before LDN dose. ((had no troubles, or effects from either medicine, but also no improvement in condition, at that time I was undergoing testing for Lymphoma, and did not know had Dysautonomia)) Have just ordered a new prescription of LDN and am going to try again to see if improvements, given am not candidate for salt loading or midrodine or Flourinef. PS- it's taken me a while to participate here on the forum, but have greatly appreciated so much reading the discussions via the mobile phone, so much valuable insight, great folks, research, experiences, and more here on Dinet.org It's an honor to finally be able to post, and share.

Rich, Just wanted to say thank you for putting your theory #3 out there. (have been discouraged about how compartmentalized medicine and treatment are in regards) Have been hoping to see something show up in forums and discussion regarding this kind of thinking