Lemonsin2lemonade- My Mom and I were both diagnosed with TLE as I had severe dysphoria ( like the flu, feel rotten ) along with cognitive problems like decreased concentration, and working memory- so severe that neuropsych testing showed a borderline MR performance IQ back then, and the doctor who did the testing recommended the school records, I reported to him, be checked, as he did not think I could have accomplished this with my tested IQ. Both my Mom and myself had abnormal BEAM ( a quantitative EEG popular then ) showing TLE. My Mom had many of the "ictal" phenomenon like deja vu, and the more pathognomic smell hallucinations of burning rubber. ( these last 30sec to 2 min., with a maximum of 30 min. ) Later we have both had EEG's showing TLE and multiple types of epileptiform discharges. Neither of us has had convulsions. My Mom has CFS/ME. She also appears to have undiagnosed hyperadrenergic pots by the poor man's tilt test recently. I have found links between POTS, CFS/ME and TLE such as this complex article .... http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022475/ Note under autonomic nervous system that " In response to postural stress, 81% of patients with ME/CFS and no controls experienced ejection fraction decreases " and under neurology that " EEG data were able to discriminate with nearly 90% accuracy patients with ME/CFS from healthy controls and from those with major depression." Also this abstract http://www.ncbi.nlm.nih.gov/pubmed/21892413 My interest in NO connects this even further as Dr. Stewart has shown the change in NO in "low flow" POTS to be neuronal nitric oxide. There are many articles on epilepsy and NO with extremely conflicting results. These are mostly in rat models-though I see myself more as a guinea pig. Both Valproic ACid and Selegiline that I was on for TLE have been shown to increase NO. Ref here... http://www.ncbi.nlm.nih.gov/pubmed/19703427 ( VPA ) and here... http://www.ncbi.nlm.nih.gov/pubmed/9721939 ( Selegiline )