I have had POTS for a year, and was recently diagnosed with AAG. I was positive for the alpha-3 ganglionic acetylcholine receptor autoantibody. There is a test called "Mayo Clinic Autoimmune Dysautonomia Evaluation" http://www.mayomedicallaboratories.com/articles/hottopics/2011/02-auto-dys-eval/index.html but most of my doctors refused to order it. I had to see 10 specialists before someone agreed to order the test, and when it was finally performed the result was positive. I then visited the Mayo Clinic neuroimmunology department, and they did a very good job, catching many things my previous doctors had missed. They also recommended immunotherapy, with IVIg or steroids, followed by azathiopine or CellCept. I am in a hospital in Germany right now and just finished my second day of IVIg (0.4 g / kg / day). I pray that it works; if not I will need plasma exchange or immunosupressants.