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@erinlia I have HPOTS and Raynauds, as well as Prinzmetal angina ( kind of Raynauds of the heart ). In the beginning of my illness they did not know about HPOTS and ordered Midodrine. It was ineffective but did not noticeably make my POTS or Raynauds worse. Once diagnosed by my autonomic specialist with HPOTS he immediately stopped the Midodrine because he said it is not the right med for my case. After many med trials I found the best relief from Carvelidol and Diltiazem ( a vasodilator ). 

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