For Anyone Who's Seen Major Improvement On Ubiquinol/ubiquinone/coq10

[res]

For anyone who's seen major improvement on ubiquinol/ubiquinone/coq10: What are your diagnoses/misdiagnoses and symptoms? I have been diagnosed with POTS and autonomic neuropathy. I have had several periods where I rapidly got worse and developed new symptoms, but I think I have been having symptoms for at least 20 years if not more (I am 33 and have been struggling to "fake normal" for as long as I can remember). Listing all my symptoms would take forever, but the most recent ones were muscle weakness that worsened with everyday activities like preparing food, and waking up in the morning with severe freezing/shocklike/burning sensations triggered by any movement. My past diagnoses include IBS, Asperger's, ADHD, and bipolar; I believe those are accurate except for the bipolar, since my symptoms were not typical and involved 3-4 days of severe low energy followed by 3-4 days of anxiety/agitation, and I believe the cycling was a consequence of forcing myself to function whenever I had any energy and then crashing. I have also had loss of appetite and extreme difficulty maintaining weight for nine years.

I began looking into ubiquinol because of overlap between many of my symptoms and mitochondrial disorders (in particular, an autism spectrum diagnosis and extreme difficulty maintaining weight, plus gastrointestinal problems and dysautonomia).

I began taking ubiquinol three weeks ago along with some other supplements, and had major improvement right away - was able to begin walking again, 3k steps the first day, then 7k, then 10k every day after that. Then, this last weekend, my husband wanted to put the ubiquinol in the fridge since it's a "squishy" supplement. Sunday I felt horrible - incredibly fatigued, barely awake, depressed, miserable. Monday and Tuesday were the same. Late Tuesday afternoon I went to take my afternoon dose, looked at the bottle, and thought "wait, this isn't my ubiquinol." I'd been taking my husband's fish oil pills by mistake! I took a double dose of ubiquinol and fifteen(!) minutes later felt completely normal again - not my crappy "normal" which is like someone else's bad day, but like other peoples' normal. I have energy, I can think clearly, no more oversensitivity to sounds when I wake up in the morning, I can listen to music again, I can have conversations, I can even exercise. Everything is different. My husband said that both the decline and the improvement have been extremely striking. I still have some orthostatic intolerance, but it is far less severe.

100mg at a time is helpful, but not as helpful as 200mg. The effects start after 10-15 minutes, last for several hours, and then decline to the point that I don't feel well enough to work, although not to the point that I can't walk places. This occurs despite my having had normal levels of Coq10 when tested in January. I had also been on Coq10 (not ubiquinol) several years ago, at a lower dose, and it did not do anything.

This seems to be extremely unusual, and I'm hoping I can find someone else who has a similar response, and who might have seen other specialists or have had other diagnoses. I am continuing to seek care because I don't know whether the ubiquinol is treating a root problem, or whether it is treating downstream effects of some underlying problem that increased in severity until I was mostly housebound for two months prior to starting ubiquinol. I also don't know what specialist I should see. I have a cooperative but not pro-active GP; he takes me seriously, and is willing to refer me to specialists, but doesn't know what specialists he should refer me to. My autonomic specialist's office is severely overloaded with patients, and they have made multiple major errors in my care and were disbelieving and uninterested when I described my improvement.

[k&ajsmom]

Wow, yr thread was perfect timing for me.i was just logging on to ask about coq10. I was just diagnosed with some other issues and told my coq10 levels were low as well and was wondering what dose to take.ive read it can cause hypotension with those of us whom already have hypotension and was worried about dosage.

I'm not much help to you're questions right now but I'm starting tonight on my supplements.I'm gonna take the lowest dose they have and work my way up to make sure there are no adverse reactions so I'll let you know if it helps. I also have been diagnosed mg or lems so i don't know what symptoms are related to what but hopefully will know soon. Good luck and will keep ya posted.=)

~Sarah

[Katybug]

I've taken b12 and/or b-complex by itself and coq10 and/or ubiquinol by itself and didn't get as much benefit from any of it as with the supplement I take now that is 200 mg of coq10, b-complex, and a few other vitamins all together. The manufacturer claims the combo is necessary for the body to use the coq10 most effectively. Since it was more cost effective and was one pill instead of several I tried it and I really do get a better quality energy. I still suffer bouts of daytime hypersomnia but my periods of energy are better. It is sold on hsn.com, CoQ10 200 by Andrew Lessman.