More Hope For Sfn

[HopeSprings]

New discoveries! My favorite line was .... "One recent study 4 and the study published in this issue of Annals of Neurology5 indicate that we are finally making inroads into the sizable block of idiopathic SFN."

http://onlinelibrary.wiley.com/doi/10.1002/ana.22666/full

[HopeSprings]

Don't know why my original link didn't work - but this is what it was about-->Nav1.7/SCN9A http://www.ncbi.nlm.nih.gov/pubmed/22275247 I dug up the post because I wanted to remember when I posted it. I remembered at the time thinking it was exciting, but probably wouldn't help me (us) now. Well, only a little over a year later, the test is available and I was able to get it done last week. I'll have the results in a month or two. And even if it's negative, they are finding more and more genes related to this so all hope is not lost! (see below). If this really explains almost 30% of cases of Idiopathic SFN, that's a lot of people and I would think good treatments will eventually follow. The testing is done through GeneDx if anyone with idiopathic SFN wants to discuss with their Doctor. I'm not sure if other labs do the testing.

"The Dutch team is continuing to seek genetic causes for the remaining cases of I-SFN that are not explained by SCN9A mutations. Faber says that they are sequencing SCN10A, which encodes the related channel Na_v1.8, and SCN11A, encoding Na_v1.9. “Certainly there will be more genes” that cause these other cases, she says. “I’m convinced of that.” From: http://www.painresearchforum.org/news/7360-nav17-mutations-move-mainstream