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Sigulair For Mcad


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I take Singulair, and it helps with my itching. It blocks leucotrienes (spelling?), just another chemical that may be involved in mast cell disease.

Not only is histamine released when a mast cell dumps, but also prostaglandins, leukotrienes and other chemicals. These can be blocked with different meds from different classes.

For example, a mast cell patient may be on aspirin, singulair, claritin and pepcid. Aspirin blocks prostaglandin, singulair blocks leukotrienes, claritin blocks histamine (H1 inhibitor) and Pepcid blocks mast cell release in the gut (H2 inhibitor).

Hope this helps.

Lindajoy

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