What Should I Do? Advice Needed.

[JoeJack101]

I was diagnosed with Mitral Valve Prolapse Syndrome & Dysautonomia at the Birmingham clinic in 2005. At the time my main problem (and the only symptom I really noticed) was a severe sensitivity to the effects drugs and herbs. It wasn't an allergic reaction, it was that I experienced the exaggerated effects of whatever it was, even by consuming the smallest amount or even touching it! And it was not in my head. It was never a sensitivity to foods or anything else. Only medicinal things. It was impossible to live like that and dangerous being so sensitive.

Move forward a couple years: I noticed that the sensitivity to drugs and herbs was completely GONE when I had anything that boosted Acetylcholine. At first, I noticed that Ashwagandha extract (which boosts acetylcholine receptor activity) made my sensitivity go away completely. Any choline supplement worked the exact same.

But here is the problem: This boost in choline or Acetylcholine leaves me dangerously fatigued all the time. So much so that I am unable to work or get anything accomplished. It's horrifying. It's basically ruined my life.

So there is a two fold problem: If I do not take Choline, I am left 1000x's more sensitive to herbs and drugs than any human alive, even touching some pills can cause the medicinal effects on my body. But this goes away if I take even just a little Choline, at which point I am no longer sensitive, but I am fatigued and exhausted all the time if I take it.

I live in the Dallas area, but I don't even know which doctor to see. I want to see a dysautonomia doctor. It's just bizarre, and I just want to have a normal life. Any help or advice is greatly appreciated. I'm desperate.

[ramakentesh]

gees sounds pretty challenging.

Ive found that my sensitivities wax and wane with my symptoms and thanfully they have died down after the start of POTS to some extent. Is there something else you can take for the fatigue when your on choline etc? caffeine?