Hello, this is my theory and my long story - short.
I have POTS for about 11 years, all begin after I use high dosage of arginine alpha ketoglutarate and citruline malate, after few month I start to feel POTS symptoms, but I didin't stop use it and after one month symptomhs increase and I start unable to tolerate exercises. Now if I try arginine alpha ketoglutarate my symptoms get much worse for about 2 months, after 2 months symptoms improve, but never disappear.
Now I'm searching medicine, supplements to reduce nitric oxide.