Several years too late to this conversation but am finding it really interesting and helpful. I have EDS/POTS and a recent diagnosis for ADHD. I had been taking ad hoc Clonazepam (once or twice a week) for restless leg so that I could sleep. When I started taking a central nervous system stimulant for my ADHD, I stopped taking the Clonazepam... for about six weeks my POTS symptoms completely disappeared! 100%! Then they came back. I had always had an uneven histamine intolerance, but it was cumulative rather than an outright allergy to specific things, and symptoms were so inconsistent that I could treat them with antihistamines as needed.... unfortunately, I have now discovered that because histamine is a neurotransmitter, CNS stimulants increase histamine production in the body. So any positive effects I get from the stimulant are erased by the antihistamine! 🙄 a histamine overload plus an inability to break it down is now messing with my menstrual cycle.
I have been taking Quercetin and DAO supplements to stabilise the mast cells and degrade excess histamine. I’m interested in Clonazepam, but worried about the long half life. I tried it last night (1mg) and slept wonderfully, but woke up a bit dizzy and I’m just waiting for the stimulant to work but I suspect that the dose may be less effective than usual.
Has anyone seen similar effects with shorter acting benzos? Or using something like Melatonin?
How Is Clonazepam Beneficial?
in Dysautonomia Discussion
Posted
Several years too late to this conversation but am finding it really interesting and helpful. I have EDS/POTS and a recent diagnosis for ADHD. I had been taking ad hoc Clonazepam (once or twice a week) for restless leg so that I could sleep. When I started taking a central nervous system stimulant for my ADHD, I stopped taking the Clonazepam... for about six weeks my POTS symptoms completely disappeared! 100%! Then they came back. I had always had an uneven histamine intolerance, but it was cumulative rather than an outright allergy to specific things, and symptoms were so inconsistent that I could treat them with antihistamines as needed.... unfortunately, I have now discovered that because histamine is a neurotransmitter, CNS stimulants increase histamine production in the body. So any positive effects I get from the stimulant are erased by the antihistamine! 🙄 a histamine overload plus an inability to break it down is now messing with my menstrual cycle.
I have been taking Quercetin and DAO supplements to stabilise the mast cells and degrade excess histamine. I’m interested in Clonazepam, but worried about the long half life. I tried it last night (1mg) and slept wonderfully, but woke up a bit dizzy and I’m just waiting for the stimulant to work but I suspect that the dose may be less effective than usual.
Has anyone seen similar effects with shorter acting benzos? Or using something like Melatonin?