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Lamby

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  1. Several years too late to this conversation but am finding it really interesting and helpful. I have EDS/POTS and a recent diagnosis for ADHD. I had been taking ad hoc Clonazepam (once or twice a week) for restless leg so that I could sleep. When I started taking a central nervous system stimulant for my ADHD, I stopped taking the Clonazepam... for about six weeks my POTS symptoms completely disappeared! 100%! Then they came back. I had always had an uneven histamine intolerance, but it was cumulative rather than an outright allergy to specific things, and symptoms were so inconsistent that I could treat them with antihistamines as needed.... unfortunately, I have now discovered that because histamine is a neurotransmitter, CNS stimulants increase histamine production in the body. So any positive effects I get from the stimulant are erased by the antihistamine! 🙄 a histamine overload plus an inability to break it down is now messing with my menstrual cycle. I have been taking Quercetin and DAO supplements to stabilise the mast cells and degrade excess histamine. I’m interested in Clonazepam, but worried about the long half life. I tried it last night (1mg) and slept wonderfully, but woke up a bit dizzy and I’m just waiting for the stimulant to work but I suspect that the dose may be less effective than usual. Has anyone seen similar effects with shorter acting benzos? Or using something like Melatonin?
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