I went with a 3DS, Wii U, and a PC! No taking sides here when my Nintendo consoles have a 'health and safety' app preinstalled, remind me to take breaks, and have Wii Fit U with an 'improve circulation' routine as a default! Good ol' PC has better specs then any console, with mods galore! If you forced me to pick, I'd say PS4 just for the crossplay thing with the Vita. I'm a sucker for screens I can take with me, they make life so much easier.
As a gamer in a family of them, I suppose I'll be the expert here! Any game needs the TV a fair amount away from you face, for PC games I just use my TV as the monitor! Being too close to the screen makes anyone sick. First person games need to have mouse sensitivity tuned down majorly to lessen the risk of the camera moving too fast, but this makes shooters really difficult! Some games, such as Skyrim, have a third person option that should make things easier. Racing games that aren't Mario Kart are a huge no most of the time, but MMOs are almost always fine. Any games with a known 'Guitar Hero Effect' or 'Tetris Effect' seem to vary day by day if I can play them or not but are generally fine until you start screaming about line pieces. Also, don't use the 3D on the 3DS! I've had it make average joes dizzy! Hope this helps!