shanying418

Oh, it is working, just perhaps too well. That's a seriously monstrous drop from just the Midodrine. If it's 60bpm sitting after taking the 5mg, what is it lying down? That change in posture could easily drop it another 10 or even 20. I've been at a lying down 47bpm average for some time now and my cardiologist isn't concerned unless it dips below 40. My lowest recorded awhile back was 37. And no, it's not a fun feeling when it gets too low. Have you also checked your blood pressure?

Yes. I've checked my blood pressure. It's within the normal range but compare to when I'm not on medication, it's actually lower. . . Any suggestions?

Hi Shan, welcome.

When you say the Midodrine drops your heart rate from 115 to 61, is that both while standing or lying down? Either way, if both those numbers were taken in the same position (posture), that's quite a huge drop from just 5mg of Midodrine. With my five POTS meds I'm lucky to keep my standing heart rates down from 150 to 120, which also means my resting heart rates are down from 65 into the 40's, that's mostly when I feel those minor heart pains.

Hi Simmy, Thanks for answering. The drop from 115 to 61 is HR while sitting down. I know it's quite a huge drop which worries me a bit. I did read from Mayo clinic that one of the rare side effects from Midodrine is slow pulse. Basically, my PCP believes the huge drop is b.c. of Midodrine but my cardio doc. seems to believe that means Midodrine is working. I'm just concerned b.c. I don't seem to feel well when my HR drops to that number. Tks again.

I can only I take 2.5mg three times a day - when I tried taking higher doses, it lowered my HR even more (vagal nerve response) ....

I take 5mg three times a day- 8am 12, 4pm. You've mentioned vegal nerve response, I'm wondering how is that defined? My HR drop from 115 to sometimes 61... though my body seems to rebel every time my HR drop to around 60 ish, my cardio doc told me it's okay and not to worry. Yet . . . I thought midodrine is not suppose to cause chest pain. . .