Report Have Pots And Just Started Plavix, Now Feel Terrible. Any Input? in Dysautonomia Discussion Posted January 9, 2016 Thanks so much for asking! The fatigue doesn't seem to be what it was the first day, but am still having a POTS flare the first half of the day. I stayed up late watching a movie with DH so that's probably contributing even though he got up with our youngest and let me sleep in. I'll try getting better rest and see if it helps.