lthomas521 Posted May 15, 2006 Report Share Posted May 15, 2006 At least in rats, iron deficiency reduces the concentration and function of the norepinephrine transporter.http://www.ncbi.nlm.nih.gov/entrez/query.f...l=pubmed_docsum Quote Link to comment Share on other sites More sharing options...
Guest tearose Posted May 16, 2006 Report Share Posted May 16, 2006 I don't yet understand the role of this NET.I too have the hyperadrenergic levels of norepinepherine however my barroreceptor reflexes don't adequately work (due to denervation) so I figure I need the high levels of norepinepherine to keep me circulating blood and O2.I don't have an iron deficiency.I guess I'm thinking I don't have a NET deficiency. I have small fiber deficits.Do you have a NET deficiency? I wonder how your dysautonomia is different from mine. Quote Link to comment Share on other sites More sharing options...
lthomas521 Posted May 16, 2006 Author Report Share Posted May 16, 2006 How did they document the denervation and small fiber deficits?I don't know for sure whether I have an NET deficiency or not.Even if you have normal numbers of norepinephrine transporters, you can end up with orthostatic problems if you take a drug that blocks norepinephrine uptake. So the question is the number and function of the transporters. Supposedly, the people at Baker Institute in Australia have addressed all these. We're all still waiting for their report. Quote Link to comment Share on other sites More sharing options...
Guest tearose Posted May 16, 2006 Report Share Posted May 16, 2006 Denervation and small fiber deficiency were diagnosed at Mayo, MN during the Thermoregulatory Sweat Test. I seem to sweat profusely from my face and neck area, and near collar bones but from my ribs on down I produce no sweat!There is also obvious bluing of my calves when I stand.I don't think I'm not uptaking my norepinepherine, rather I'm profusely producing it to rapidly attempt to get O2 to the brain and other vital organs. Quote Link to comment Share on other sites More sharing options...
Sunfish Posted May 16, 2006 Report Share Posted May 16, 2006 i am extrememly iron deficient but don't have high levels of norepi at all...mine are normal. i also have denervation, small fiber neuropathy, etc. melissa Quote Link to comment Share on other sites More sharing options...
leah1321 Posted May 18, 2006 Report Share Posted May 18, 2006 I have very low iron and hyperadrenergic POTS. Quote Link to comment Share on other sites More sharing options...
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