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Can't Take More Than 2.5Mg Midodrine?


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Hi, I was just dx'd with POTs two weeks ago and my neuro doc (before getting into Stanford) started me on trying 2.5mg Midodrine 2/day and it's not working too much in helping my symptoms. It is increasing my BP too much so I can't take an increased dose. So, my neuro recommended for now to try going off Midodrine for 5 days to see if I want to be on it or not and then start on 20mg Propranolol 2/day. I have Orthostatic Hypotension, but the extra salt and Nuun tablet intake alone is raising my BP enough to help that. Has anyone had a similar experience?

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I asked my Neuro that and he said that he wasn't sure lowering my HR was going to help with my symptoms but maybe if my BP went up a little bit more it might help...?

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Yes, I have dx POTs as well, so I have both. My resting pulse on tilt table was about 77 and then during the upright went from 99 to 148.

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