Pps Not Pots

[EGorman]

I'm still going through test and the runaround with doctors. All I know so far is that I have Dysautonomia (more specifically Paradoxical Parasympathetic Syndrome or PPS), but not POTS. I can't find any info on it anywhere. Does anyone have this (I hope not for your sake)? I just need info so I know what to do or expect. Plus, I had an ANSAR test, not the tilt-table. Anyone have that? Thanks!

[Goschi]

Hi, EGorman!

I was diagnosed with POTS (multiple times, 3 TTTs) and have never heard about PPS, to be honest. I didn't find too much information on this condition on the Internet either.

Would you mind to tell about some of the typical symptoms you experience? Are they very different from POTS...?

I haven't had an ANSAR-test, heard about it from your post for the first time too.

[gjensen]

I had not heard of this either. I will look into it. It will be new to me.

[EGorman]

Paradoxical Parasympathetic Syndrome (or PPS) is an odd functioning of the parasympathetic system of the ANS. This is very involved, but here is some technical info on it:

The Need For Central Vs Peripheral Therapeutic Action

In general, there is an oppositional or See-Saw relationship between the two autonomic branches:

sympathetics (red) and parasympathetics (blue). Normal balance and normal responses to sympathetic and parasympathetic responses are shown below in the first three diagrams. The fourth diagram models the abnormal condition known as paradoxic para sympathetic syndrome (PPS). The paradox is that the parasympathetics are abnormally responding (abnormally increasing) to a sympathetic challenge.

Clinically, this serves to destabilize patients’ responses to disease and therapy. It destabilizes because rather than falling away first, the parasympathetics are in creasing, forcing a the sympathetics to increase more than usual. These frequency, excessive sympathetics surges can lead to hypertensive states and all of the secondary conditions that result. PPS is found in over 50% of our database (over 12,000 patient studies), and seems to be

associated with three or more of the following symptoms:

• Difficulty falling asleep (can take up to several hours) or wake frequently during the night;

• Poor circulation;

• Restless leg syndrome or night-time edema;

• GI upset (GERD, frequent diarrhea or constipation);

• Depression, anxiety, panic-attacks or bipolar-like symptoms;

• Frequent morning migraines or headaches;

• Frequent morning cognitive difficulties (memory, function);

• Chronic pain syndromes (including Fibormyalgia);

• Syndromes that include chronic fatigue;

• (If 35-45 y;/o female) menopause-like symptoms; or

• Frequent dizziness upon standing.

Therapeutically, the difficulty is that these surges look like a primary sympathetic abnormality when EKG, heart rate, or blood pressure is measured. If treated as such using typical anti-adrenergic therapy like (peripheral) beta-blockers (.e.g., Toprol, Metaprolol), the anti-adrenergic therapy

(1) reduces any endogenous sympathetic opposition, thereby

(2) further strengthening the parasympathetics, which then

(3) respond even more abnormally, ultimately

(4) forcing the sympathetics to respond even more. The sympathetics respond even more because the brain still

demands its blood and since the therapy does not block all sympathetic channels, the body can find alternate pathways to deliver blood to the brain; thus defeating the efficacy of the therapy.

Edited August 12, 2014 by corina

[EGorman]

Well the last post didn't translate well in the copy and paste. Here is the link to the ANSAR info PDF:

http://www.ans-hrv.com/Interp_Complete.pdf

[corina]

EGorman, I fixed your post. Having said that, the link contains much more information of course, thanks for sharing!

[Goschi]

Thanks Gorman, for the link! That's a completely new area for me!! Does PPS exclude POTS (and vice versa)?

[EGorman]

PPS can be in addition to POTS I believe. The ANSAR test and the information it provides is very new and groundbreaking. The link above is super informative, if you can wade through all the medical jargon (which most dysautonomiacs can). I'm still looking for a doctor, although there is a specialist in my city, I have not been able to reach him. I strongly suggest looking into the ANSAR test. Here is the website (very good info!)

http://www.ans-hrv.com/

[EGorman]

And thank you to Corina for fixing my post! I am really looking into a ton of info for research, since most doctors are uninformed about PPS, so I'll try to keep posting any info I find