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Renin, Angiostensin, Pooling, And Vanderbilt


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http://stoppotsvirginia.blogspot.com/2012/08/hydration-salt-and-peeing-renin.html

"""""""Facilitates norepinephrine (a type of adrenaline) release from sympathetic nerve endings and inhibits norepinephrine re-uptake by nerve endings (prevents it from being reabsorbed), thereby enhancing sympathetic adrenergic function (again - helps keep your veins squeezing to circulate blood, and keeps levels of adrenalin normal in your system. So too much Angiotensin II may INCREASE norepinepherine, which the hyperPOTS group, and many POTS people in general have higher levels

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This goes back to the gorilla in the room:

Are these biochemical changes compensatory or maladaptive?

As much as it is said that you must find your sub-type of POTS, I think that trialing drugs until you find something that works for you is a valid approach. Some people have had success with ARBs.

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