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Evoxac And Dysautonomia/syncope Side Effects


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I was recently diagnosed with Vocal Cord Dysfunction, subseqently had nasolaryngoscopy and found to also have chronic laryngitis thought to be from GERD that Rx isn't handling enough (also have gastroparesis issues), and chronic post nasal drip, immunocompromization (starting IV Ig), and found membranes to be extremely dry. Otolaryngologist said some of my Rx's cause dryness (I take Midodrine 10 mg 3 X/day that still leaves me with low BP) and a water pill once every 4 to 7 days depending how much I've had the legs down/what I'd been doing--guage the need by the amount of pooling in legs. He initiates Evoxac that the says will help increase the secretions in mouth, gut, sinuses, throat, etc. He said it would help with my lips, too (which I'd never mentioned as every doc/dentist I've asked--they peel off constantly to my face and are raw--since they all tell me they don't know 'must be an autoimmune thing').

His RN and paper they give me about the med list most common side effects of this med as: fainting, excessive sweating, nausea/vomiting, diarrhea, heart rate too fast/too slow/irregular, etc. Seems like these are all the symptoms of my near syncope/syncopal episodes. After just a third dose (and not knowing if due to med or incidental from headache that turned migraine) yesterday morn, I'd felt the BP dropping when I had got up to void thru the night and could not get to sleep til after 4 a.m. When I did get up and brush teeth, had to rush to get down and BP was 75/44 HR 78. This morn when I got up it was 86/58 and HR 103 (getting out of bed/brushing teeth). My BP is usually borders low when I get up but am wondering if this is tipping the envelope a bit.

Anyone familiar with this? Does it just take a while for body to 'acclimate' to the drug? I'm still waiting on cardiac specialist to initiate another agent to get me hypertensive since I didn't tolerate the Mestinon. I had vomiting and severe nausea yesterday but am not sure if that was from the migraine or dysautonomia being exacerbated.

The University otolarygologist was aware of my dysautonomia but still felt this Rx was warranted (and at $85 co-pay for me).

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Yes, I was prescribed this for a serious dry mouth issue, but I refused to take it. I did not want to create more problems for myself by taking it. I did not trust my ability to handle it.

Thank you, futurehope.

This scares me but how red and inflammed the larynx/cords were and the difficulty with swallowing/breathing is a scarey thing too. I have to take some speech therapy--therapist told me she would teach me exercises to help with the breathing (things in the throat shut off at the end of the exhalation phase that makes me feel like I am not getting in a good breath. I have to see him back in a couple of mos. for repeat scope. He wrote 6 refills. The nurse told me the Rx is used to treat Sjorgrens (but he was not diagnosing Sjorgrens--but I sure do have a lot of the symptoms). I'm really iffy on this one but trying to keep close watch and wait to see if incidental, if the body acclimates or if it makes things worse (right now, am thinking it's making my pressure a little lower but it may just be coincidental since I am sick again).

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