Midodrine And Agitation?

[mkoven]

My ans doc thought that while pursuing further answers about what's going on, we could safely increase my midodrine. I"d been taking 5mgs, 4x day. She wants me at 7.5, 4x a day. My experience in the past is that with each increase, I get a huge jittery/anxious rush initially, that eventually wears off. In the interim, I feel like I want to jump out of my skin! This morning I just increased the dose to 6.25, and feel it. I feel so hyper and speedy-- and admittedly less lightheaded.

My bp is still okay. I got one reading of 120/70, others around 110/65. I checked supine, and it was 109/65.

Anyone else? If I thought it were safe (stress test tomorrow), I feel like I want to run around the block to get all this hyperness out of my system!!!!

[maryfw]

I seem to have the opposite reaction. If I dont take mine on time I get jittery.

mary

[goldicedance]

When you say "junp out of your skin," do you refer to chills, goose bumps and head tingling? I experienced that while on Midodrine. Midodrine is very fast acting and perhaps that intensifies the reaction.

I put up with it for several years because it made me functionable. Eventually I had a "relapse." Since then, I have been on Mestinon time release.

Have you tried Mestinon? Mestinon seemed more to stabilize my blood pressure so I could stand up.

Lois

[mkoven]

Unfortunately, I'm allergic to mestinon. Five years ago, a doc speculated that I might have myasthenia gravis, and tried me on it. After two days-- major rash-- sigh.

The jitteriness is bette now, but seems to come on whenever I increase the dose.