Hi Issie, Glad to hear you are doing better. I have tried Zantac with my son but it makes his vocal tics much worse. The tramadol aslo makes his vocal tics worse. I thought I read somewhere that tramadol effects dopamine levels. I have to be careful when adding supplements or medication. When my son had the Cunningham Panel test in Novemer 2013, it revealed he had high dopamine, CamKinese and GM1 ganglioside. There is a connection between dopamine and glutamate. High CamKinese causes major prob