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http://en.wikipedia....ion#cite_note-1 Endothelial dysfunction is a systemic pathological state of the endothelium (the inner lining of blood vessels) and can be broadly defined as an imbalance between vasodilating and vasoconstricting substances produced by (or acting on) the endothelium.[1] Normal functions of endothelial cells include mediation of coagulation, platelet adhesion, immune function and control of volume and electrolyte content of the intravascular and extravascular spaces. Endothelial dysfunction can result from and/or contribute to several disease processes, as occurs in septic shock, hypertension, hypercholesterolaemia, diabetes, it can also result from environmental factors, such as from smoking tobacco products and exposure to air pollution. I found a test to check for this. If there is another test for this let me know. This may be a big help for all of us. It affect every level of POTS. The test http://www.itamar-me...om/EndoPAT.html Prevention and treatment Endothelial function can be improved significantly by exercise and improved diet. A study published in 2005 has determined that a positive relationship exists between the consumption oftrans fat (commonly found in hydrogenated products such as margarine and the development of endothelial dysfunction.[3] Other factors have been identified as improving endothelial function and include cessation of smoking, loss of weight and treatment of hypertension and hypercholesterolemia amongst other things. Some studies have found antioxidants,potassium[4] and arginine supplementation to restore impaired endothelial function.
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