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Showing results for tags 'Missouri group'.
I have a special interest since my nephrologist says that POTS probably caused my kidney issues... I'd love feedback on the quality of these docs if anyone has seen them: Cardiorenal Med. 2011;1(2):113-122. Epub 2011 Apr 15. An Emerging Role for Understanding Orthostatic Hyp'er'tension in the Cardiorenal Syndrome. Buddineni JP, Chauhan L, Ahsan ST, Whaley-Connell A. Source Division of General Internal Medicine, University of Missouri-Columbia School of Medicine, Columbia Mo., USA. Abstract Orthostatic hypertension (OHT) is a clinically important problem increasingly recognized in persons with borderline hypertension, diabetes mellitus, and autonomic neuropathies, and in the elderly. Moreover, the association of OHT with progression of target end-organ damage, especially coronary heart disease and chronic kidney disease (CKD), and the attendant increased cardiovascular disease (CVD) and CKD risk, is gaining attention but is still underappreciated. There are various mechanisms that contribute to the development of OHT: excessive vascular adrenergic sensitivity, baroreceptor reflex abnormalities, and inappropriate activation of the renin-angiotensin-aldosterone system, which are also mechanisms that lead to cardiorenal metabolic disease (CRS). While the evidence is compelling for the clinical importance of OHT, more investigation is needed to evaluate the effects of OHT on CKD and CVD. The notion that the development of OHT is a risk factor for the development of CRS raises the need for further clinical and investigational attention to this clinical dilemma. PMID: 22258398 [PubMed] PMCID: PMC3101511