Rita, I also have POTS, along with many other problems, possible endometriosis being one of them. I have been on the pill for 11yrs now...I am only 25, but my period problems started right from the start. I take cryselle-28 in continuous cycles (no period for 3-6 months). I still get worsening POTS symptoms/migraines once a month, but it is considerably less severe with the pill. GOOD LUCK! Ivy