Background: I like most in here, was in the shape of my life, enjoying my early 30's and all of a sudden this weird illness hitme. I went from Dr. to Dr. and they tried everything from Thyroid tests to Adrenal tests and of course kept calling it anxiety. I went to a CFS clinic at Harborview in Seattle and my new family doc sent me for a TTT and I passed out after 7 minutes (iv of saline only no adrenaline). He then sent me to this website and gave me a prescription of Midodrine. That night I felt weird... Had a major headache and felt like I was on fire. for the next week, I felt like my heart was going to explode and my head hurt so bad, I could even drive. I quit taking and today is the 1st day off of it. My chest still aches a bit, but no head problems or anything. I have severe leg tingles and feel completely fatigued, but better than when I was on the Midodrine. Anyone else have problems with it? Are there other meds instead? I called my Dr. but just left messages. He had me on 5mg (1/2 in am and 1/2 in afternoon) and was going to increase it from there.... thanks! Brian