Report Confused after “positive” tilt-table test in Dysautonomia Discussion Posted September 10, 2018 43 minutes ago, StayAtHomeMom said: POTS always has an underlying cause. It is not a disease but rather a cluster of symptoms. I still have not found mine but I have a high suspicion it is autoimmune since that runs so high in my family. Finding the underlying cause can be hard but in theory if you take care of the underlying cause then your POTS symptoms can resolve. Key word: in theory. Have your doctor's done a urine catacholmine test yet? If not I would ask for it. It can determine if you have HyperPOTS. Actually, I asked the Dr if he could test me for hyperadrenergic POTS, and he ordered the blood test. When I asked him if it would be the catecholamine test he denied and said he would like to do this (cortisol) test first. But now he wats to do the 24-hour urine collection, and yes, I will ask him to check my catecholamines as well.... I didn't know that there are various causes for POTS and that they can be individually diagnosed--thus, I thought a treatment is based on dealing with the symptoms instead of attacking the cause! That sounds great! Means there's reason for hope! I hope you'll find another cause than autoimmune so that you can attack the issue at the roots! Good luck to you!