Adjusting to Clonidine, Not Sure in Dysautonomia Discussion Posted Sunday at 11:27 PM · Report reply Metoprolol is the only thing that has improved sleep much for me. It partially quiets the pounding tachycardia. I do sometimes use melatonin, theanine, or valerian root to "cover up the sick feelings" and make it easier to sleep despite them. Magnesium taurate or glycinate has seemed to help, too. I haven't tried clonidine although I am sure it would help - my BP is far too low for me to use it.