I started metoprolol and quickly stopped it because it made my exercise routine difficult. No other Pots meds, but on blood pressure med, Lipisnore, effexor, vitamin d, testrosterone, coQ10, Lovaza, multivitmin and aspirin. Several episodes a day of standing up and dizzy. Soooo much fun! Dr says drink water. I drink 2-3 liters a day.I exercise three times a week with cardio and weight lifting. Nothing seems to make a detent in the frequency of the episodes.