Hi Guys, I'm a long time reader first time poster from Australia. The interesting thing about my case is that I have had the majority of these symptoms since birth. I am getting a TTT done next week to confirm POTS but I am close to certain that this form of Dysautonomia has plagued me for 24 years. Poor/Slow Circulation Brain Fog Fatigue Depression Emotionless Anxiety/SNS overdrive Cold hands/feet No libido Light/sound sensitivity Allergies Anaphylaxis - Peanuts Immune Dysfunction IBS Inability to stand for long periods My supine heart rate is 85 and blood pressure 125/70. On standing HR goes up about 25-30 beats and BP goes up as well. After a period of time my feet get very sore on standing, I get breathless and tired. I have tried elimination diets, vitamins, herbs and thyroid/adrenal hormone replacement. None of which have helped me. Hydrocortisone lowered my sensitivities somewhat but nothing else. When friends motivate me to come out I can muster up the strength and sometimes look like a normal person when with them, but If i over do it I get sick with a cold or sinus infection and need to recover. Most of the time i'm house bound feeling horrible. So after being told I am depressed (which I am because ive been sick for so long) or told I fall into the chronic fatigue basket and can't be helped. I decided to take research into my own hands. After having two phone consults with Dr Holtorf CFS expert from America and trying his recommended treatments to no avail, I came across a CFS website that mentioned POTS. Every single symptom they mentioned I pretty much had since I could remember. Eg Problem taking showers, crossing my legs on sitting and standing etc... I then found this website and have done hours of research thanks to you wonderful people. So I am happy to at least have found a diagnosable and relatively treatable illness now that I can tell people. Even if I don't quite fail the TTT I will be still certain that i have a certain variation of POTS. I am seeing a Cardiologist who has an open mind and is willing to try any treatment that will improve my quality of life. Based on my symptoms and individual characteristics i believe i fall into the Low Flow category or Hyper category. In contrast to many of you here, I prefer warmer, more humid weather and despise cold weather. My veins are extremely vasoconstricted and I am very cold sensitive. I don't get any circulation to my skin or extremities, leaving me quite pale. I have never been able to relax, and I hope that some pharmacological treatments can help me do this and in turn improve my peripheral circulation. As sad as this sounds, I will take even a 15-20 percent improvement because I have no idea what feeling well is supposed to be like. I hope that in the coming years we can increase awareness about this condition and in turn find a cure. In my opinion there very well could be an autoimmune cause behind this and that POTS and CFS are just variations of Dysautonomia under the same umbrella. Look forward to discussing everything there is about this condition with you all. Thanks