I first noticed the blood pooling while taking 4 weeks of Levaquin in Spring 2009. I was then diagnosed with POTS in Spring 2010. Prior to 2009 I was not complaining of POTS associated symptoms. In hindsight, they existed in a mild form but the Lyme and Babesia symptoms - chills, fevers, swollen lymph nodes, sore throats, fatigue, muscle aches, etc were most pronounced. Now those are all gone, and POTS is predominant.