Hi everyone - I have been diagnosed with POTS and EDS 3 by Prof Mathias. I am also pretty certain I have a mast cell disorder though when my tryptase was tested it was 11 (has to be over 20 for mastocytosis here in the UK). My big issue is food - am down to only a few foods and even they cause major reactions - flsuhing, tachycardia, faintness, itchiness, severe muscle and joint pain, you name it. I also get angioedema. i am having a real job getting anyone to link the three diseases and get me a MCAD diagnosis. i went to see the top mastocytosis doctor in london and while I am sure he is great for that he doesn't really 'do' MCAD. Has anyone had any success here in the UK with mast cell side of things?