I was in the hospital for almost a month this fall, and was given my first PICC in the hospital because IVs weren't working. I was getting 200 mL an hour for about a month and a half, then went down to 175 an hour for a week, then now I am at 125. We are trying to wean down to nothing, but I'm guessing I will end up getting a few liters a week in the long run. I went through a PICC in one week (it clotted and looked infected), then a mid-line in two weeks before getting my tunneled catheter in my chest. I get two 12 hour infusions a day, and my home nurse comes once a week to change the dressing and check my vitals. The high doses of fluids seemed to help, but now I'm not seeing as much of a difference. Most other POTS people I know just get a couple liters a week.