I take 5mg three times a day- 8am 12, 4pm. You've mentioned vegal nerve response, I'm wondering how is that defined? My HR drop from 115 to sometimes 61... though my body seems to rebel every time my HR drop to around 60 ish, my cardio doc told me it's okay and not to worry. Yet . . . I thought midodrine is not suppose to cause chest pain. . .