I have had panic/POTs problems. I would first suggest talking to your specialist/physician, etc. Currently I am undergoing progressive relaxation therapy. My therapist has actually worked with Dr. Grubb on some research with this a while ago. I've only started it this week, and it has helped out tremendously with calming my system down. It actually is a series of muscle constrictions/releases and breathing. So, if you are not big on medicines, this might be something that is helpful.