Hi, I'm new here, but have been reading many of the posts and recognizing so many situations and symptoms. I'm a POTS caregiver/family member: My son Daniel has been sick since he was 15--and he'll be 21 in late May. I'm amazed at how many similarities there are between his condition and ones I've seen here! Just to respond to this post: Daniel definitely has brisk reflexes: the neurologists have commented on this. It means, for example, that his leg kicks up faster and harder than usual when they tap on the knee. This doesn't seem to be a problem in itself, but I think from what the neuros say that it is a symptom of other problems in the nervous system. I.e., the nerves are conducting faster than they should. We see it as a finding that validates--for any doctors who recognize only "objective" findings--that there is something wrong with Daniel's nervous system, even though the things that bother him (like chronic pain, fatigue, POTS itself....) aren't part of the reflexes. I can also empathize with your story about the endocrinologists. Daniel has lots of endo problems that have finally been diagnosed--diabetes insipidus, adrenal failure, and hypogonadism (very low testosterone, since he's on the male side of the aisle)--but often the endocrinologists were the last to recognize these problems. I remember once when Dan was in the hospital with intestines that had slowed to the point of possible obstruction. He was on the gastroenterology service and one of the GI interns had the idea of testing for adrenal failure. The consulting endocrinologist had a literal fit, arguing with the GI doctors in Dan's room and insisting that this couldn't possibly be a problem; the endo resident even cancelled one of the tests that the GI doctors ordered and for which blood had already been drawn. But the GI docs persisted and, lo and behold, Dan clearly had an adrenal insufficiency. Treating him for that, unfortunately, didn't solve all of his problems but it did help. I look forward to reading more from everyone on the forum. I've already learned a lot and hope I can contribute to you as well! Debby