My son (17) has extreme chronic nausea for the last 4 years, and sporadically 2 years before that. He was diagnosed with tachygastria and atypical GERD. He threw up Zorfan and every other anti-nausea drug. You name it, we've tried it. What helped was finding Dr. Kenneth Koch, a specialist in chronic unexplained nausea, at Wake Forest in Winston-Salem, NC, who did an EGG, an electrogastrogram. We found out that his gastric rhythmn was going a mile a minute. He had the motility test as well, but that turned out normal. He had huge levels of acid in his esphogus, but fortunately no pain. He is on Domperidone (for motility) and Prevacid (for acid). Domperidone has given him some relief. We have to order it from Canada. He is still so nauseated that he can't attend school, but he is able to leave the house now and then for a short outing. It was searching for an explanation as to why he had tachygastria that led us to Dr. Hasan Abdallah in Fairfax, VA. He diagnosed my son with POTS in November 2008. We're doing the trial and error thing now in hopes we can find something that will alleviate the tachygastria, which we hope in turn will reduce the acid, which are the major problems, along with the numbing fatigue. I hope you find help. Will keep you in my thoughts and will post again if we find any help for nausea.