Guest Anne L Posted August 29, 2006 Report Share Posted August 29, 2006 Has anyone taken domperidone for gastroparesis? Just diagnosed after EGD and GES. I can't take Reglan, so doc has prescribed this. I''m reluctant to try it b/c while my belly is slow, my colon reacts to the least little bit of food. The pharmacist didn't push it after I mentioned the dysautonomia. My inclination is not to mess with anything else. Your experience/ opinion please. This is all very new to me.Thanks.Anne L Quote Link to comment Share on other sites More sharing options...
cardiactec Posted August 29, 2006 Report Share Posted August 29, 2006 hi there,i was also recently diagnosed with gastroparesis after EGD and GES and prescribed domperidone. i cant take it though because after talking to my cardio about it, he told me it interracts with my beta blocker (sotalol)....gastroparesis can be do to a multple of conditions/problems including dysautonomia (not sure why the pharmacist wouldnt push for the med because you mentioned dysuatonomia, since gastroparesis is a form or added condition of dysautonomias)............i would say it doesnt hurt to try it (meaning it cant kill you). i know it stinks to have to pick between one symptom or another, but which is worst for you, the gastroparesis symptoms or the spastic colon? if you suffer nausea/vomiting from the paresis, i would take the colon issues any day over nausea/vomiting! i hope you get some relief of your symptoms soon. sorry to hear you were diagnosed with gastroparesis....take care! Quote Link to comment Share on other sites More sharing options...
DSM3KIDZ Posted August 29, 2006 Report Share Posted August 29, 2006 I also have gastroparesis and it seems to be getting more popular on these boards. I tried domperidone for about 2 months. At 2 months I kept having these weird dizzy spells. It felt like an anxiety attack but I never had one so I'm not sure. Anyways after stopping it these episodes went away ao I'm not sure if the domperidone was the cause or not.My only symptom of gastroparesis is the horrible nausea so I'll take a nausea med when that acts up. What are your sx from it?Good luck and it's worth a trial period.I also take reglan as needed since I can tolerate 5 mg.Dayna Quote Link to comment Share on other sites More sharing options...
stellakitty Posted August 29, 2006 Report Share Posted August 29, 2006 Annie,My daughter takes this, she was prescribed by a GI dr. with alot of experience with Dysautonomia...She was on Reglan, he did not want her to take Reglan b/c it can cause "movement disorders", (I don't remember what specifically), anywho, she says it is a huge improvement over the Reglan. She is "going" more fequently and does not "taste" the previous night dinner...The DOWNSIDE; this drug is not "approved" for use in the US, (we are the only country?), I have to have it "compounded" at a local phar., it is not covered by our insurance plan, this is another 60 bucks a month for me to squeeze out of this squashed turnip.A Quote Link to comment Share on other sites More sharing options...
Tanzanite Posted August 29, 2006 Report Share Posted August 29, 2006 I take metoclompramide which is an anti-sickness drug and also speeds up the rate of things going through the stomach. Domperidone just turns off the vomit centre, not sure why they give you this instead of metoclompramide. Quote Link to comment Share on other sites More sharing options...
juliegee Posted August 29, 2006 Report Share Posted August 29, 2006 Hi Anne -I am also very active on the Yahoo International Gastroparesis Website on behalf of my 13 y/o son. I know MANY there with dysautonomia, who safely take domperidone. Why not give it a try? If you have any negative side effects, you may want to try liquid erythromycin as an alternative. In tiny pediatric doses, it irritates the GI tract into emptying more quickly. My son has been on "E" for almost a year now- prescribed by his motility specialist at Johns Hopkins.Yes, domperidone is not available in the US. But, it is sold all over the world, OTC in many countries and is much, much safer than reglan- the prokinectic of choice in the US. Domperidone doesn't cross the blood/brain barrier, unlike reglan, and works only on the GI tract. Many members of the GP site, with their doctor's prescriptions, order it at "The Global Drugstore" online. They have fast, reliable, economical service. Best of luck. I know, from watching my son suffer, how debilitating gastroparesis can be. But, it can be managed effectively.Julie Quote Link to comment Share on other sites More sharing options...
juliegee Posted August 29, 2006 Report Share Posted August 29, 2006 Tanzanite-I hope you get this message. Metoclompramide is the generic form of reglan. I've learned from watching my son suffer and from hanging out at the Yahoo Gastroparesis website- this is a BAD drug- especially for someone with POTS. My son was on this drug for 5 months before we had to switch him. Everyone of the GP site warned me that reglan would cause negative side effects and boy, were they right. I have been on that site for a year and a half and NOONE has been able to tolerate reglan long term. My son developed anxiety and he couldn't stop moving when he was on that drug. He would just walk circles around a room, never stopping. Reglan is also associated with depresssion and tachycardia episodes. There are better prokinetic/anti-nausea alternatives for you to try. Domperidone and erythromycin can be very effective prokinetics. And zofran or kytril are great for fighting severe nausea w/o sedative effects. Best of luck to you!Julie I take metoclompramide which is an anti-sickness drug and also speeds up the rate of things going through the stomach. Domperidone just turns off the vomit centre, not sure why they give you this instead of metoclompramide. Quote Link to comment Share on other sites More sharing options...
Sunfish Posted August 29, 2006 Report Share Posted August 29, 2006 for the most part, ditto to everything julie (mack's mom) said. reglan/metoclompramide does wonders for some, especially in the short term, but can also be VERY problematic. it was helpful for me for a short while but i then started having some scary side effects and now cannot take it at all. another major caveat about some of the side effects/ reactions that reglan can bring about do not always go away when the med is stopped but can instead be permanant.about domperidone, i've not had any problems with it though my motility is slow from top to bottom. i have severe gastroparesis & have after trying just about everything else have been taking domperidone since april of this year. unfortunately it hasn't done much for me in the way of benefit but there are A LOT of people for whom it is a lifesaver. hope this helps, melissa Quote Link to comment Share on other sites More sharing options...
juliegee Posted August 30, 2006 Report Share Posted August 30, 2006 Hi There!Ditto to everything Melissa said. I forgot to mention that, for all of it's negative side effects, reglan helped my son be able to eat. He had lost 15 lbs in a very short period of time. So, it does work- but can have very negative side effects AND some of those side effects persist beyond the time you stop taking the med. Please check out alternatives if you are on reglan.Julie Tanzanite-I hope you get this message. Metoclompramide is the generic form of reglan. I've learned from watching my son suffer and from hanging out at the Yahoo Gastroparesis website- this is a BAD drug- especially for someone with POTS. My son was on this drug for 5 months before we had to switch him. Everyone of the GP site warned me that reglan would cause negative side effects and boy, were they right. I have been on that site for a year and a half and NOONE has been able to tolerate reglan long term. My son developed anxiety and he couldn't stop moving when he was on that drug. He would just walk circles around a room, never stopping. Reglan is also associated with depresssion and tachycardia episodes. There are better prokinetic/anti-nausea alternatives for you to try. Domperidone and erythromycin can be very effective prokinetics. And zofran or kytril are great for fighting severe nausea w/o sedative effects. Best of luck to you!Julie I take metoclompramide which is an anti-sickness drug and also speeds up the rate of things going through the stomach. Domperidone just turns off the vomit centre, not sure why they give you this instead of metoclompramide. Quote Link to comment Share on other sites More sharing options...
Guest Anne L Posted August 30, 2006 Report Share Posted August 30, 2006 Thanks so much for your helpful replies.(That's what my last post was supposed to say.)Because I'm taking a beta blocker, have an over-active colon, and tend to be what Doctor Spock called "an occasional child" (will have......) Explanation for the younger of us.I usually have the side effects listed in the small print at the bottom of the page. Dysautonomia? or just my own weird thing?Reglan left me with full-blown parkingsonism. After six uears I still have most of the stuff except the extrapyramidal (facial) movement part. SO....I'm going to hold off on Domperidone. My prescription will be on file for a year. See the doc September21 and see how crazy he gets because I haven't taken it. His office called with GES results: "delayed gastric emptying (period) Duh.........Anne L Quote Link to comment Share on other sites More sharing options...
Tanzanite Posted September 1, 2006 Report Share Posted September 1, 2006 Message received I have been on metoclompramide/reglan for years. No problems here, works well for me. My OH is on it too and he's fine too. Quote Link to comment Share on other sites More sharing options...
morgan617 Posted September 2, 2006 Report Share Posted September 2, 2006 what works for some is a killer for others. I took reglan a long time ago, but just couldn't tolerate the side effects. My son can't either.He takes domperidone without any problems and it does help. My gi doesn't want me taking anything, I mean like either one, so I just deal with non moving top and speedy gonzales lower..... Quote Link to comment Share on other sites More sharing options...
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