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This is a questions for  the female posters: I have hyperadrenergic POTS which caused Interstitial Cystitis ( chronic bladder inflammation ). This has been getting worse with symptoms of overactive bladder. I have tried all meds and diet changes recommended for this but the symptoms are worsening. I saw my PCP yesterday and asked about meds for this condition, which are Detrol or Ditropan. He said he would prescribe them for me but he wasn't sure if they would affect my POTS since they apparently work on the nervous system. So here is my question: do any of you take these meds and have you experienced any negative effects with your POTS symptoms from them? I am hesitant to try if there is a chance they cause any POTS symptoms to reappear or worsen. Thank you in advance for any replies. 

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